Turnover of Focal Adhesions and Cancer Cell Migration

Cells are usually surrounded by the extracellular matrix (ECM), and adhesion of the cells to the ECM is a key step in their migration through tissues. Integrins are important receptors for the ECM and form structures called focal adhesions (FAs). Formation and disassembly of FAs are regulated dynami...

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Bibliographic Details
Main Authors: Makoto Nagano, Daisuke Hoshino, Naohiko Koshikawa, Toshifumi Akizawa, Motoharu Seiki
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2012/310616