Increase Paclitaxel Sensitivity to Better Suppress Serous Epithelial Ovarian Cancer via Ablating Androgen Receptor/Aryl Hydrocarbon Receptor-ABCG2 Axis

Increase Paclitaxel Sensitivity to Better Suppress Serous Epithelial Ovarian Cancer via Ablating Androgen Receptor/Aryl Hydrocarbon Receptor-ABCG2 Axis

Background: Epithelial ovarian cancer (EOC) is one of the most lethal gynecological malignancies and presents chemoresistance after chemotherapy treatment. Androgen receptor (AR) has been known to participate in proliferation. Yet the mechanisms of the resistance of this drug and its linkage to the...

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Bibliographic Details
Main Authors: Wei-Min Chung, Yen-Ping Ho, Wei-Chun Chang, Yuan-Chang Dai, Lumin Chen, Yao-Ching Hung, Wen-Lung Ma
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cancers
Subjects:
ovarian cancer serous subtype
androgen receptor
ABCG2
aryl hydrocarbon receptor
paclitaxel resistance
Online Access:https://www.mdpi.com/2072-6694/11/4/463

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https://www.mdpi.com/2072-6694/11/4/463

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