Interaction of HLA Class II rs9272219 and TMPO rs17028450 (Arg690Cys) Variants Affects Neuromyelitis Optica Spectrum Disorder Susceptibility in an Admixed Mexican Population

Interaction of HLA Class II rs9272219 and TMPO rs17028450 (Arg690Cys) Variants Affects Neuromyelitis Optica Spectrum Disorder Susceptibility in an Admixed Mexican Population

Neuromyelitis Optica Spectrum Disorder (NMOSD) is a demyelinating autoimmune disease of the central nervous system, more prevalent in individuals of non-European ancestry. Few studies have analyzed genetic risk factors in NMOSD, and HLA class II gene variation has been associated NMOSD risk in vario...

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Main Authors: Sandra Rosas-Madrigal, María Teresa Villarreal-Molina, José Flores-Rivera, Verónica Rivas-Alonso, Luis Rodrigo Macias-Kauffer, Graciela Ordoñez, María del Carmen Chima-Galán, Víctor Acuña-Alonzo, Gastón Macín-Pérez, Rodrigo Barquera, Julio Granados, Ricardo Valle-Rios, Teresa Corona, Alessandra Carnevale, Sandra Romero-Hidalgo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Genetics
Subjects:
NMOSD
TMPO
HLA
genetic interaction
rs17028450
rs9272219
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.647343/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.647343/full

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