Contributions of histone H3 nucleosome core surface mutations to chromatin structures, silencing and DNA repair.

Contributions of histone H3 nucleosome core surface mutations to chromatin structures, silencing and DNA repair.

Histone H3 mutations in residues that cluster in a discrete region on the nucleosome surface around lysine 79 of H3 affect H3-K79 methylation, impair transcriptional silencing in subtelomeric chromatin, and reveal distinct contributions of histone H3 to various DNA-damage response and repair pathway...

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Bibliographic Details
Main Authors: Michel Fink, Jeffrey S Thompson, Fritz Thoma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22053185/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22053185/pdf/?tool=EBI

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