Early treatment versus expectative management of patent ductus arteriosus in preterm infants: a multicentre, randomised, non-inferiority trial in Europe (BeNeDuctus trial)

Early treatment versus expectative management of patent ductus arteriosus in preterm infants: a multicentre, randomised, non-inferiority trial in Europe (BeNeDuctus trial)

Abstract Background Much controversy exists about the optimal management of a patent ductus arteriosus (PDA) in preterm infants, especially in those born at a gestational age (GA) less than 28 weeks. No causal relationship has been proven between a (haemodynamically significant) PDA and neonatal com...

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Bibliographic Details
Main Authors: Tim Hundscheid, Wes Onland, Bart van Overmeire, Peter Dijk, Anton H. L. C. van Kaam, Koen P. Dijkman, Elisabeth M. W. Kooi, Eduardo Villamor, André A. Kroon, Remco Visser, Daniel C. Vijlbrief, Susanne M. de Tollenaer, Filip Cools, David van Laere, Anne-Britt Johansson, Catheline Hocq, Alexandra Zecic, Eddy Adang, Rogier Donders, Willem de Vries, Arno F. J. van Heijst, Willem P. de Boode
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Pediatrics
Subjects:
Prematurity
Patent ductus arteriosus
Neonatal intensive care unit
Ibuprofen
Expectative management
Ductal ligation
Online Access:http://link.springer.com/article/10.1186/s12887-018-1215-7

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http://link.springer.com/article/10.1186/s12887-018-1215-7

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