Analysis of the native structure, stability and aggregation of biotinylated human lysozyme.

Fibril formation by mutational variants of human lysozyme is associated with a fatal form of hereditary non-neuropathic systemic amyloidosis. Defining the mechanistic details of lysozyme aggregation is of crucial importance for understanding the origin and progression of this disease and related mis...

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Bibliographic Details
Main Authors: Minkoo Ahn, Erwin De Genst, Gabriele S Kaminski Schierle, Miklos Erdelyi, Clemens F Kaminski, Christopher M Dobson, Janet R Kumita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3500338?pdf=render