Evidence for antigenic seniority in influenza A (H3N2) antibody responses in southern China.

A key observation about the human immune response to repeated exposure to influenza A is that the first strain infecting an individual apparently produces the strongest adaptive immune response. Although antibody titers measure that response, the interpretation of titers to multiple strains--from th...

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Bibliographic Details
Main Authors: Justin Lessler, Steven Riley, Jonathan M Read, Shuying Wang, Huachen Zhu, Gavin J D Smith, Yi Guan, Chao Qiang Jiang, Derek A T Cummings
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22829765/pdf/?tool=EBI