Wild-Type Mitochondrial DNA Copy Number in Urinary Cells as a Useful Marker for Diagnosing Severity of the Mitochondrial Diseases.

Wild-Type Mitochondrial DNA Copy Number in Urinary Cells as a Useful Marker for Diagnosing Severity of the Mitochondrial Diseases.

The genotype-phenotype relationship in diseases with mtDNA point mutations is still elusive. The maintenance of wild-type mtDNA copy number is essential to the normal mitochondrial oxidative function. This study examined the relationship between mtDNA copy number in blood and urine and disease sever...

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Bibliographic Details
Main Authors: Hui Liu, Yinan Ma, Fang Fang, Ying Zhang, Liping Zou, Yanling Yang, Sainan Zhu, Songtao Wang, Xuefei Zheng, Pei Pei, Lin Li, Hairong Wu, Yang Xiao, Yufeng Xu, Liwen Wang, Yanyan Cao, Hong Pan, Yu Qi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3695014?pdf=render

Internet

http://europepmc.org/articles/PMC3695014?pdf=render

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