KCC2-dependent Steady-state Intracellular Chloride Concentration and pH in Cortical Layer 2/3 Neurons of Anesthetized and Awake Mice

Neuronal intracellular Cl− concentration ([Cl−]i) influences a wide range of processes such as neuronal inhibition, membrane potential dynamics, intracellular pH (pHi) or cell volume. Up to date, neuronal [Cl−]i has predominantly been studied in model systems of reduced complexity. Here, we implemen...

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Bibliographic Details
Main Authors: Juan C. Boffi, Johannes Knabbe, Michaela Kaiser, Thomas Kuner
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Cellular Neuroscience
Subjects:
pH
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2018.00007/full