Widespread Exaptation of L1 Transposons for Transcription Factor Binding in Breast Cancer

L1 transposons occupy 17% of the human genome and are widely exapted for the regulation of human genes, particularly in breast cancer, where we have previously shown abundant cancer-specific transcription factor (TF) binding sites within the L1PA2 subfamily. In the current study, we performed a comp...

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Bibliographic Details
Main Authors: Jiayue-Clara Jiang, Joseph A. Rothnagel, Kyle R. Upton
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
L1
Online Access:https://www.mdpi.com/1422-0067/22/11/5625