Early Sirolimus Gel Treatment May Diminish Angiofibromas and Prevent Angiofibroma Recurrence in Children With Tuberous Sclerosis Complex

Early Sirolimus Gel Treatment May Diminish Angiofibromas and Prevent Angiofibroma Recurrence in Children With Tuberous Sclerosis Complex

Introduction: Tuberous sclerosis complex (TSC) is a multisystem neurocutaneous disorder. Angiofibromas (AF), fibrous plaques, and hypopigmented macules are the major skin findings in TSC. Topical sirolimus reduces the volume and redness of AF and other skin findings. However, the efficacy of early i...

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Bibliographic Details
Main Authors: Tohru Okanishi, Ayataka Fujimoto, Hideo Enoki, Masaaki Ogai
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Medicine
Subjects:
angiofibroma
sirolimus
fibrous plaque
hypopigmented macules
tuberous sclerosis complex
early treatment
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00001/full

Internet

https://www.frontiersin.org/article/10.3389/fmed.2020.00001/full

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