ZGRF1 promotes end resection of DNA homologous recombination via forming complex with BRCA1/EXO1

ZGRF1 promotes end resection of DNA homologous recombination via forming complex with BRCA1/EXO1

Abstract To maintain genomic stability, the mammalian cells has evolved a coordinated response to DNA damage, including activation of DNA repair and cell cycle checkpoint processes. Exonuclease 1 (EXO1)-dependent excision of DNA ends is important for the initiation of homologous recombination (HR) r...

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Bibliographic Details
Main Authors: Shuang Yan, Man Song, Jie Ping, Shu-ting Lai, Xiao-yu Cao, Chen-Jun Bai, Da-Fei Xie, Hua Guan, Shan-shan Gao, Ping-Kun Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00633-7

Internet

https://doi.org/10.1038/s41420-021-00633-7

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