Safety and Feasibility of Antibiotic De-escalation in Critically Ill Children With Sepsis – A Prospective Analytical Study From a Pediatric ICU

Introduction: De-escalation is the key to balance judicious antibiotic usage for life-threatening infections and reducing the emergence of antibiotic resistance caused by antibiotic overuse. Robust evidence is lacking regarding the safety of antibiotic de-escalation in culture negative sepsis.Materi...

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Bibliographic Details
Main Authors: Vasudha Battula, Ravi Kumar Krupanandan, P. Senthur Nambi, Bala Ramachandran
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Pediatrics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2021.640857/full