Genes involved in vasoconstriction and vasodilation system affect salt-sensitive hypertension.

The importance of excess salt intake in the pathogenesis of hypertension is widely recognized. Blood pressure is controlled primarily by salt and water balance because of the infinite gain property of the kidney to rapidly eliminate excess fluid and salt. Up to fifty percent of patients with essenti...

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Main Authors: Lorena Citterio, Marco Simonini, Laura Zagato, Erika Salvi, Simona Delli Carpini, Chiara Lanzani, Elisabetta Messaggio, Nunzia Casamassima, Francesca Frau, Francesca D'Avila, Daniele Cusi, Cristina Barlassina, Paolo Manunta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3090407?pdf=render