Tyrosine-phosphorylated caveolin-1 blocks bacterial uptake by inducing Vav2-RhoA-mediated cytoskeletal rearrangements.

Certain bacterial adhesins appear to promote a pathogen's extracellular lifestyle rather than its entry into host cells. However, little is known about the stimuli elicited upon such pathogen host-cell interactions. Here, we report that type IV pili (Tfp)-producing Neisseria gonorrhoeae (P(+)GC...

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Bibliographic Details
Main Authors: Jan Peter Boettcher, Marieluise Kirchner, Yuri Churin, Alexis Kaushansky, Malvika Pompaiah, Hans Thorn, Volker Brinkmann, Gavin Macbeath, Thomas F Meyer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2927421?pdf=render