Genetic Variants in Cytosolic Phospholipase A2 Associated With Nonsteroidal Anti-Inflammatory Drug–Induced Acute Urticaria/Angioedema

Genetic Variants in Cytosolic Phospholipase A2 Associated With Nonsteroidal Anti-Inflammatory Drug–Induced Acute Urticaria/Angioedema

Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the main triggers of drug hypersensitivity reactions, probably due to their high consumption worldwide. The most frequent type of NSAID hypersensitivity is NSAID cross-hypersensitivity, in which patients react to NSAIDs from different chemical...

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Bibliographic Details
Main Authors: Raquel Jurado-Escobar, Inmaculada Doña, José Triano-Cornejo, James R. Perkins, Natalia Pérez-Sánchez, Almudena Testera-Montes, Marina Labella, Joan Bartra, José J. Laguna, Miguel Estravís, José A. G. Agúndez, María J. Torres, José A. Cornejo-García
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
NSAID cross-hypersensitivity
urticaria/angioedema
cytosolic phospholipase A2
polymorphisms
arachidomic acid
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.667824/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.667824/full

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