Vaccination against influenza with recombinant hemagglutinin expressed by Schizochytrium sp. confers protective immunity.

For the rapid production of influenza vaccine antigens in unlimited quantities, a transition from conventional egg-based production to cell-based and recombinant systems is required. The need for higher-yield, lower-cost, and faster production processes is critical to provide adequate supplies of in...

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Bibliographic Details
Main Authors: Anne-Cécile V Bayne, David Boltz, Carole Owen, Yelena Betz, Goncalo Maia, Parastoo Azadi, Stephanie Archer-Hartmann, Ross Zirkle, J Casey Lippmeier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3634000?pdf=render