Calcium Phosphate Bone Cements Including Sugar Surfactants: Part Two—Injectability, Adhesive Properties and Biocompatibility
Addition of sugar surfactants, sucrose fatty acid esters and alkylpolyglucosides to a calcium phosphate cement, designed for bone reconstruction, is described. Thanks to their adsorption at the surface of the calcium phosphate particles, the sugar surfactants allowed a full injectability and brought...
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Online Access: | http://www.mdpi.com/1996-1944/3/12/5111/ |
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doaj-b1c05100c869490d961e829fde233a332020-11-25T01:36:24ZengMDPI AGMaterials1996-19442010-12-013125111512910.3390/ma3125111Calcium Phosphate Bone Cements Including Sugar Surfactants: Part Two—Injectability, Adhesive Properties and BiocompatibilityFabienne Briand-MesangeStéphane GonçalvesHelène AutefageAriane BercierOlivier LignonJuliette FitremannAddition of sugar surfactants, sucrose fatty acid esters and alkylpolyglucosides to a calcium phosphate cement, designed for bone reconstruction, is described. Thanks to their adsorption at the surface of the calcium phosphate particles, the sugar surfactants allowed a full injectability and brought a very good workability. Injectability was measured by monitoring force-distance curves. With some of the selected sugar surfactants adhesive properties of the cement pastes were also observed, which were measured by tack tests. Finally, some properties related to biological applications are described, including gentamicine release and osteoblast viability experiments. The whole study demonstrates that addition of these mild surfactants improved several properties of the calcium phosphate cement, without impairing function. http://www.mdpi.com/1996-1944/3/12/5111/calcium phosphatesurfactantsugarinjectabilityadhesivenesssticky |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Fabienne Briand-Mesange Stéphane Gonçalves Helène Autefage Ariane Bercier Olivier Lignon Juliette Fitremann |
spellingShingle |
Fabienne Briand-Mesange Stéphane Gonçalves Helène Autefage Ariane Bercier Olivier Lignon Juliette Fitremann Calcium Phosphate Bone Cements Including Sugar Surfactants: Part Two—Injectability, Adhesive Properties and Biocompatibility Materials calcium phosphate surfactant sugar injectability adhesiveness sticky |
author_facet |
Fabienne Briand-Mesange Stéphane Gonçalves Helène Autefage Ariane Bercier Olivier Lignon Juliette Fitremann |
author_sort |
Fabienne Briand-Mesange |
title |
Calcium Phosphate Bone Cements Including Sugar Surfactants: Part Two—Injectability, Adhesive Properties and Biocompatibility |
title_short |
Calcium Phosphate Bone Cements Including Sugar Surfactants: Part Two—Injectability, Adhesive Properties and Biocompatibility |
title_full |
Calcium Phosphate Bone Cements Including Sugar Surfactants: Part Two—Injectability, Adhesive Properties and Biocompatibility |
title_fullStr |
Calcium Phosphate Bone Cements Including Sugar Surfactants: Part Two—Injectability, Adhesive Properties and Biocompatibility |
title_full_unstemmed |
Calcium Phosphate Bone Cements Including Sugar Surfactants: Part Two—Injectability, Adhesive Properties and Biocompatibility |
title_sort |
calcium phosphate bone cements including sugar surfactants: part two—injectability, adhesive properties and biocompatibility |
publisher |
MDPI AG |
series |
Materials |
issn |
1996-1944 |
publishDate |
2010-12-01 |
description |
Addition of sugar surfactants, sucrose fatty acid esters and alkylpolyglucosides to a calcium phosphate cement, designed for bone reconstruction, is described. Thanks to their adsorption at the surface of the calcium phosphate particles, the sugar surfactants allowed a full injectability and brought a very good workability. Injectability was measured by monitoring force-distance curves. With some of the selected sugar surfactants adhesive properties of the cement pastes were also observed, which were measured by tack tests. Finally, some properties related to biological applications are described, including gentamicine release and osteoblast viability experiments. The whole study demonstrates that addition of these mild surfactants improved several properties of the calcium phosphate cement, without impairing function. |
topic |
calcium phosphate surfactant sugar injectability adhesiveness sticky |
url |
http://www.mdpi.com/1996-1944/3/12/5111/ |
work_keys_str_mv |
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