Pilea umbrosa ameliorate CCl4 induced hepatic injuries by regulating endoplasmic reticulum stress, pro-inflammatory and fibrosis genes in rat

Pilea umbrosa ameliorate CCl4 induced hepatic injuries by regulating endoplasmic reticulum stress, pro-inflammatory and fibrosis genes in rat

Abstract Background Pilea umbrosa (Urticaceae) is used by local communities (district Abbotabad) for liver disorders, as anticancer, in rheumatism and in skin disorders. Methods Methanol extract of P. umbrosa (PUM) was investigated for the presence of polyphenolic constituents by HPLC-DAD analysis....

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Bibliographic Details
Main Authors: Irum Naz, Muhammad Rashid Khan, Jawaid Ahmed Zai, Riffat Batool, Zartash Zahra, Aemin Tahir
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Environmental Health and Preventive Medicine
Subjects:
Liver
Antioxidant
ER stress
Cytokines
RT-PCR
Online Access:http://link.springer.com/article/10.1186/s12199-020-00893-2

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http://link.springer.com/article/10.1186/s12199-020-00893-2

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