Developmental signalling in maintenance and regulation of cancer stem cells

Tissue stem cells self-renew throughout the life of an organism thereby maintaining tissue homeostasis and prevent cancer. The major signalling pathways such as Wnt, Notch and Sonic hedgehog control the stem cell regulation and their deregulation leads to cancer. Recent evidences showed that there e...

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Bibliographic Details
Main Authors: Sweta Dash, Raghava Reddy Sunkara, Sanjeev K Waghmare
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Biomedical Research Journal
Subjects:
emt
Online Access:http://www.brjnmims.org/article.asp?issn=2349-3666;year=2015;volume=2;issue=1;spage=37;epage=56;aulast=Dash;type=0