4-Bromophenacyl bromide specifically inhibits rhoptry secretion during Toxoplasma invasion.
Toxoplasma gondii is a eukaryotic parasite of the phylum Apicomplexa that is able to infect a wide variety of host cells. During its active invasion process it secretes proteins from discrete secretory organelles: the micronemes, rhoptries and dense granules. Although a number of rhoptry proteins ha...
Main Authors: | Sandeep Ravindran, Melissa B Lodoen, Steven H L Verhelst, Matthew Bogyo, John C Boothroyd |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-12-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2780294?pdf=render |
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