Significance and progress in detection of HBV cccDNA in peripheral blood mononuclear cells
Hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) is an intermediate replicative episome which is stable and not easy to eliminate. cccDNA serves as the template for HBV replication and plays an important role in persistence of HBV infection in hepatocytes, and it is also a biomarker o...
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Format: | Article |
Language: | zho |
Published: |
Editorial Department of Journal of Clinical Hepatology
2014-08-01
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Series: | Linchuang Gandanbing Zazhi |
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Online Access: | http://www.lcgdbzz.org/qk_content.asp?id=6032&ClassID=86141319 |