Significance and progress in detection of HBV cccDNA in peripheral blood mononuclear cells

Hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) is an intermediate replicative episome which is stable and not easy to eliminate. cccDNA serves as the template for HBV replication and plays an important role in persistence of HBV infection in hepatocytes, and it is also a biomarker o...

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Bibliographic Details
Main Author: CAI Shaoping
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Hepatology 2014-08-01
Series:Linchuang Gandanbing Zazhi
Subjects:
Online Access:http://www.lcgdbzz.org/qk_content.asp?id=6032&ClassID=86141319