Synthesis of some 3,5-diarylisoxazoline derivatives in ionic liquids media

Biologically active isoxazoline derivatives were efficiently synthesized in excellent yields and in less reaction time using mild, effective and environmentally friendly butylmethylimidazolium bromide as solvent and catalyst. By use of this catalyst isoxazoline derivatives are produced via cycli...

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Main Authors: Safaei-Ghomi Javad, Ghasemzadeh Ali Mohammad
Format: Article
Language:English
Published: Serbian Chemical Society 2012-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2012/0352-51391200001S.pdf
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spelling doaj-b36c0e38d8374fadaaf05801f6a7e2a02020-11-24T23:45:57ZengSerbian Chemical Society Journal of the Serbian Chemical Society0352-51392012-01-0177673373910.2298/JSC110831001SSynthesis of some 3,5-diarylisoxazoline derivatives in ionic liquids mediaSafaei-Ghomi JavadGhasemzadeh Ali MohammadBiologically active isoxazoline derivatives were efficiently synthesized in excellent yields and in less reaction time using mild, effective and environmentally friendly butylmethylimidazolium bromide as solvent and catalyst. By use of this catalyst isoxazoline derivatives are produced via cyclization reaction of chalcone and hydroxylamine hydrochloride in ionic liquids media. The separation of the product was facile and the catalyst could be separated and recycled. Our method is very quick, safe and avoids the use of hazardous and expensive reagents and solvents.http://www.doiserbia.nb.rs/img/doi/0352-5139/2012/0352-51391200001S.pdfisoxazolinecyclization reactionionic liquidsbutylmethylimidazolium bromidemulti-component reactionsbiological activities
collection DOAJ
language English
format Article
sources DOAJ
author Safaei-Ghomi Javad
Ghasemzadeh Ali Mohammad
spellingShingle Safaei-Ghomi Javad
Ghasemzadeh Ali Mohammad
Synthesis of some 3,5-diarylisoxazoline derivatives in ionic liquids media
Journal of the Serbian Chemical Society
isoxazoline
cyclization reaction
ionic liquids
butylmethylimidazolium bromide
multi-component reactions
biological activities
author_facet Safaei-Ghomi Javad
Ghasemzadeh Ali Mohammad
author_sort Safaei-Ghomi Javad
title Synthesis of some 3,5-diarylisoxazoline derivatives in ionic liquids media
title_short Synthesis of some 3,5-diarylisoxazoline derivatives in ionic liquids media
title_full Synthesis of some 3,5-diarylisoxazoline derivatives in ionic liquids media
title_fullStr Synthesis of some 3,5-diarylisoxazoline derivatives in ionic liquids media
title_full_unstemmed Synthesis of some 3,5-diarylisoxazoline derivatives in ionic liquids media
title_sort synthesis of some 3,5-diarylisoxazoline derivatives in ionic liquids media
publisher Serbian Chemical Society
series Journal of the Serbian Chemical Society
issn 0352-5139
publishDate 2012-01-01
description Biologically active isoxazoline derivatives were efficiently synthesized in excellent yields and in less reaction time using mild, effective and environmentally friendly butylmethylimidazolium bromide as solvent and catalyst. By use of this catalyst isoxazoline derivatives are produced via cyclization reaction of chalcone and hydroxylamine hydrochloride in ionic liquids media. The separation of the product was facile and the catalyst could be separated and recycled. Our method is very quick, safe and avoids the use of hazardous and expensive reagents and solvents.
topic isoxazoline
cyclization reaction
ionic liquids
butylmethylimidazolium bromide
multi-component reactions
biological activities
url http://www.doiserbia.nb.rs/img/doi/0352-5139/2012/0352-51391200001S.pdf
work_keys_str_mv AT safaeighomijavad synthesisofsome35diarylisoxazolinederivativesinionicliquidsmedia
AT ghasemzadehalimohammad synthesisofsome35diarylisoxazolinederivativesinionicliquidsmedia
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