Metabolic modulation regulates cardiac wall morphogenesis in zebrafish

Metabolic modulation regulates cardiac wall morphogenesis in zebrafish

During cardiac development, cardiomyocytes form complex inner wall structures called trabeculae. Despite significant investigation into this process, the potential role of metabolism has not been addressed. Using single cell resolution imaging in zebrafish, we find that cardiomyocytes seeding the tr...

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Bibliographic Details
Main Authors: Ryuichi Fukuda, Alla Aharonov, Yu Ting Ong, Oliver A Stone, Mohamed El-Brolosy, Hans-Martin Maischein, Michael Potente, Eldad Tzahor, Didier YR Stainier
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-12-01
Series:eLife
Subjects:
zebrafish
trabeculation
heart development
cardiomyocytes
metabolism
glycolysis
Online Access:https://elifesciences.org/articles/50161

Internet

https://elifesciences.org/articles/50161

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