Phenylbutyrate interferes with the Fanconi anemia and BRCA pathway and sensitizes head and neck cancer cells to cisplatin

<p>Abstract</p> <p>Background</p> <p>Cisplatin has been widely used to treat head and neck cancer. One of the clinical limitations with this treatment, however, is that tumors that are initially responsive to cisplatin later acquire resistance. We have recently shown th...

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Bibliographic Details
Main Authors: Ljungman Mats, Burkitt Kyunghee
Format: Article
Language:English
Published: BMC 2008-03-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/7/1/24