Targeting Genome Integrity in <i>Mycobacterium Tuberculosis</i>: From Nucleotide Synthesis to DNA Replication and Repair

Targeting Genome Integrity in <i>Mycobacterium Tuberculosis</i>: From Nucleotide Synthesis to DNA Replication and Repair

<i>Mycobacterium tuberculosis</i> (MTB) is the causative agent of tuberculosis (TB), an ancient disease which still today causes 1.4 million deaths worldwide per year. Long-term, multi-agent anti-tubercular regimens can lead to the anticipated non-compliance of the patient and increased...

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Bibliographic Details
Main Authors: Riccardo Miggiano, Castrese Morrone, Franca Rossi, Menico Rizzi
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Molecules
Subjects:
<i>mycobacterium tuberculosis</i>
nucleotide synthesis
dna replication
dna repair
antitubercular drugs
novel drug targets
Online Access:https://www.mdpi.com/1420-3049/25/5/1205

Internet

https://www.mdpi.com/1420-3049/25/5/1205

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