Response of striosomal opioid signaling to dopamine depletion in 6-hydroxydopamine-lesioned rat model of Parkinson’s disease: a potential compensatory role.

Response of striosomal opioid signaling to dopamine depletion in 6-hydroxydopamine-lesioned rat model of Parkinson’s disease: a potential compensatory role.

The opioid peptide receptors consist of three major subclasses, namely, mu, delta and kappa (MOR, DOR and KOR, respectively). They are involved in the regulation of striatal dopamine functions, and increased opioid transmissions are thought to play a compensatory role in altered functions of the bas...

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Bibliographic Details
Main Authors: Hidetaka eKoizumi, Ryoma eMorigaki, Shinya eOkita, Shinji eNagahiro, Ryuji eKaji, Masanori eNakagawa, Satoshi eGoto
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Dopamine
Parkinson Disease
Striatum
opioid receptors
striosome
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00074/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00074/full

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