Topology and robustness in the Drosophila segment polarity network.

A complex hierarchy of genetic interactions converts a single-celled Drosophila melanogaster egg into a multicellular embryo with 14 segments. Previously, von Dassow et al. reported that a mathematical model of the genetic interactions that defined the polarity of segments (the segment polarity netw...

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Bibliographic Details
Main Author: Nicholas T Ingolia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2004-06-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC423129?pdf=render