Regulation of bestrophins by Ca2+: a theoretical and experimental study.

Bestrophins are a recently discovered family of Cl(-) channels, for which no structural information is available. Some family members are activated by increased intracellular Ca2+ concentration. Bestrophins feature a well conserved Asp-rich tract in their COOH terminus (Asp-rich domain), which is ho...

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Bibliographic Details
Main Authors: Agata Kranjc, Federico W Grillo, Juraj Rievaj, Anna Boccaccio, Fabio Pietrucci, Anna Menini, Paolo Carloni, Claudio Anselmi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2650406?pdf=render