Insights from deconvolution of cell subtype proportions enhance the interpretation of functional genomic data.

Cell subtype proportion variability between samples contributes significantly to the variation of functional genomic properties such as gene expression or DNA methylation. Although the impact of the variation of cell subtype composition on measured genomic quantities is recognized, and some innovati...

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Bibliographic Details
Main Authors: Yu Kong, Deepa Rastogi, Cathal Seoighe, John M Greally, Masako Suzuki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215987