The role of acquired immunity in the spread of human papillomavirus (HPV): explorations with a microsimulation model.

The role of acquired immunity in the spread of human papillomavirus (HPV): explorations with a microsimulation model.

BACKGROUND: Knowledge of the natural history of human papillomavirus (HPV), in particular the role of immunity, is crucial in estimating the (cost-) effectiveness of HPV vaccination and cervical cancer screening strategies, because naturally acquired immunity after clearing an infection may already...

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Bibliographic Details
Main Authors: Suzette M Matthijsse, Joost van Rosmalen, Jan A C Hontelez, Roel Bakker, Inge M C M de Kok, Marjolein van Ballegooijen, Sake J de Vlas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4314063?pdf=render

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