TAFA4, a Chemokine-like Protein, Modulates Injury-Induced Mechanical and Chemical Pain Hypersensitivity in Mice

TAFA4, a Chemokine-like Protein, Modulates Injury-Induced Mechanical and Chemical Pain Hypersensitivity in Mice

C-low-threshold mechanoreceptors (C-LTMRs) are unique among C-unmyelinated primary sensory neurons. These neurons convey two opposite aspects of touch sensation: a sensation of pleasantness, and a sensation of injury-induced mechanical pain. Here, we show that TAFA4 is a specific marker of C-LTMRs....

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Bibliographic Details
Main Authors: Marie-Claire Delfini, Annabelle Mantilleri, Stéphane Gaillard, Jizhe Hao, Ana Reynders, Pascale Malapert, Serge Alonso, Amaury François, Christian Barrere, Rebecca Seal, Marc Landry, Alain Eschallier, Abdelkrim Alloui, Emmanuel Bourinet, Patrick Delmas, Yves Le Feuvre, Aziz Moqrich
Format: Article
Language:English
Published: Elsevier 2013-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713005214

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http://www.sciencedirect.com/science/article/pii/S2211124713005214

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