Impact of the repurposed drug thonzonium bromide on host oral-gut microbiomes

Abstract Drug repurposing is a feasible strategy for the development of novel therapeutic applications. However, its potential use for oral treatments and impact on host microbiota remain underexplored. Here, we assessed the influences of topical oral applications of a repurposed FDA-approved drug,...

Full description

Bibliographic Details
Main Authors: Aurea Simon-Soro, Dongyeop Kim, Yong Li, Yuan Liu, Tatsuro Ito, Kenneth R. Sims, Danielle S. W. Benoit, Kyle Bittinger, Hyun Koo
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-020-00181-5