NAD+ in Alzheimer’s Disease: Molecular Mechanisms and Systematic Therapeutic Evidence Obtained in vivo

NAD+ in Alzheimer’s Disease: Molecular Mechanisms and Systematic Therapeutic Evidence Obtained in vivo

Mitochondria in neurons generate adenosine triphosphate (ATP) to provide the necessary energy required for constant activity. Nicotinamide adenine dinucleotide (NAD+) is a vital intermediate metabolite involved in cellular bioenergetics, ATP production, mitochondrial homeostasis, and adaptive stress...

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Bibliographic Details
Main Authors: Xinshi Wang, Hai-Jun He, Xi Xiong, Shuoting Zhou, Wen-Wen Wang, Liang Feng, Ruiyu Han, Cheng-Long Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
NAD+
NAD+ precursors
Alzheimer’s disease
aging
molecular mechanisms
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.668491/full

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