The effects of heterogeneity on Simon Phase II clinical trial design operating characteristics

Christopher N Barnes1, Shesh N Rai21Department of Bioinformatics and Biostatistics, University of Louisville, 2Biostatistics Shared Facility, James Graham Brown Cancer Center, Louisville, KentuckyAbstract: The homogeneity assumption of a Simon Phase II clinical trial is commonly violated due to exce...

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Bibliographic Details
Main Authors: Christopher N Barnes, Shesh N Rai
Format: Article
Language:English
Published: Dove Medical Press 2010-07-01
Series:Open Access Journal of Clinical Trials
Online Access:http://www.dovepress.com/the-effects-of-heterogeneity-on-simon-phase-ii-clinical-trial-design-o-a4750