Determination of piperaquine concentration in human plasma and the correlation of capillary versus venous plasma concentrations.

<b>Background: </b>A considerable challenge in quantification of the antimalarial piperaquine in plasma is carryover of analyte signal between assays. Current intensive pharmacokinetic studies often rely on the merging of venous and capillary sampling. Drug levels in capillary plasma may...

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Bibliographic Details
Main Authors: Norah Mwebaza, Vincent Cheah, Camilla Forsman, Richard Kajubi, Florence Marzan, Erika Wallender, Grant Dorsey, Philip J Rosenthal, Francesca Aweeka, Liusheng Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0233893