TMEA, a Polyphenol in Sanguisorba officinalis, Promotes Thrombocytopoiesis by Upregulating PI3K/Akt Signaling

TMEA, a Polyphenol in Sanguisorba officinalis, Promotes Thrombocytopoiesis by Upregulating PI3K/Akt Signaling

Thrombocytopenia is closely linked with hemorrhagic diseases, for which induction of thrombopoiesis shows promise as an effective treatment. Polyphenols widely exist in plants and manifest antioxidation and antitumour activities. In this study, we investigated the thrombopoietic effect and mechanism...

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Bibliographic Details
Main Authors: Hong Li, Xueqin Jiang, Xin Shen, Yueshan Sun, Nan Jiang, Jing Zeng, Jing Lin, Liang Yue, Jia Lai, Yan Li, Anguo Wu, Long Wang, Dalian Qin, Feihong Huang, Qibing Mei, Jing Yang, Jianming Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
thrombocytopenia
Sanguisorba officinalis L.
PI3K
megakaryocyte differentiation
3
3′
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.708331/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.708331/full

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