Inhibition of sterol biosynthesis in animal cells by 14 alpha-alkyl-substituted 15-oxygenated sterols.
Reported herein are the results of investigations of the effects of a number of 14 alpha-alkyl-substituted 15-oxygenated sterols, prepared by chemical synthesis, on sterol biosynthesis and the levels of 3-hydroxy-3-methylglutaryl CoA reductase activity in L cells and in primary cultures of fetal mou...
Main Authors: | G J Schroepfer, Jr, E J Parish, M Tsuda, D L Raulston, A A Kandutsch |
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Format: | Article |
Language: | English |
Published: |
Elsevier
1979-11-01
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Series: | Journal of Lipid Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S002222752040001X |
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