Drug resistance in natural isolates of Leishmania donovani s.l. promastigotes is dependent of Pgp170 expression.

Resistance of pathogens to drugs is a growing concern regarding many diseases. Parasites like Leishmania, Plasmodium and Entamoeba histolytica; and neoplastic cells, present the multidrug-resistant phenotype rendering chemotherapy ineffective. The acquired resistance of Leishmania to antimony has ge...

Full description

Bibliographic Details
Main Authors: Ippokratis Messaritakis, Vasiliki Christodoulou, Apostolos Mazeris, Eleni Koutala, Antonia Vlahou, Sevasti Papadogiorgaki, Maria Antoniou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23776486/?tool=EBI