Vascular Lipidomic Profiling of Potential Endogenous Fatty Acid PPAR Ligands Reveals the Coronary Artery as Major Producer of CYP450-Derived Epoxy Fatty Acids
A number of oxylipins have been described as endogenous PPAR ligands. The very short biological half-lives of oxylipins suggest roles as autocrine or paracrine signaling molecules. While coronary arterial atherosclerosis is the root of myocardial infarction, aortic atherosclerotic plaque formation i...
Main Authors: | Matthew L. Edin, Fred B. Lih, Bruce D. Hammock, Scott Thomson, Darryl C. Zeldin, David Bishop-Bailey |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-04-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/9/5/1096 |
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