A role for Set1/MLL-related components in epigenetic regulation of the Caenorhabditis elegans germ line.

The methylation of lysine 4 of Histone H3 (H3K4me) is an important component of epigenetic regulation. H3K4 methylation is a consequence of transcriptional activity, but also has been shown to contribute to "epigenetic memory"; i.e., it can provide a heritable landmark of previous transcri...

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Bibliographic Details
Main Authors: Tengguo Li, William G Kelly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3063756?pdf=render