Elevated plasma glypicans are associated with organ failure in patients with infection

Abstract Background Increased vascular permeability is a key feature in the pathophysiology of sepsis and the development of organ failure. Shedding of the endothelial glycocalyx is increasingly being recognized as an important pathophysiological mechanism but at present it is unclear if glypicans c...

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Bibliographic Details
Main Authors: Jane Fisher, Adam Linder, Peter Bentzer
Format: Article
Language:English
Published: SpringerOpen 2019-01-01
Series:Intensive Care Medicine Experimental
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40635-018-0216-z