Protection against renal ischemia–reperfusion injury in vivo by the mitochondria targeted antioxidant MitoQ

Ischemia–reperfusion (IR) injury to the kidney occurs in a range of clinically important scenarios including hypotension, sepsis and in surgical procedures such as cardiac bypass surgery and kidney transplantation, leading to acute kidney injury (AKI). Mitochondrial oxidative damage is a significant...

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Bibliographic Details
Main Authors: Anna J. Dare, Eleanor A. Bolton, Gavin J. Pettigrew, J. Andrew Bradley, Kourosh Saeb-Parsy, Michael P. Murphy
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231715000397