Dissecting Outcomes: Should Cytoreductive Nephrectomy Be Performed for Patients With Metastatic Renal Cell Carcinoma With Sarcomatoid Dedifferentiation?

Dissecting Outcomes: Should Cytoreductive Nephrectomy Be Performed for Patients With Metastatic Renal Cell Carcinoma With Sarcomatoid Dedifferentiation?

BackgroundIt is highly contested whether cytoreductive nephrectomy for treating advanced renal cell carcinoma (RCC) with sarcomatoid features (sRCC) benefits overall survival. Patients with sRCC are known to have a poor prognosis, and these tumors have a more aggressive biology than those without sa...

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Bibliographic Details
Main Authors: Jacob J. Adashek, Yumeng Zhang, William Paul Skelton, Alyssa Bilotta, Jad Chahoud, Logan Zemp, Jiannong Li, Jasreman Dhillon, Brandon Manley, Philippe E. Spiess
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
renal cell cancer
sarcomatoid dedifferentiation
cytoreductive nephrectomy
kidney cancer
systemic therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.627025/full

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https://www.frontiersin.org/articles/10.3389/fonc.2020.627025/full

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