Large scale immune profiling of infected humans and goats reveals differential recognition of Brucella melitensis antigens.

Large scale immune profiling of infected humans and goats reveals differential recognition of Brucella melitensis antigens.

Brucellosis is a widespread zoonotic disease that is also a potential agent of bioterrorism. Current serological assays to diagnose human brucellosis in clinical settings are based on detection of agglutinating anti-LPS antibodies. To better understand the universe of antibody responses that develop...

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Bibliographic Details
Main Authors: Li Liang, Diana Leng, Chad Burk, Rie Nakajima-Sasaki, Matthew A Kayala, Vidya L Atluri, Jozelyn Pablo, Berkay Unal, Thomas A Ficht, Eduardo Gotuzzo, Mayuko Saito, W John W Morrow, Xiaowu Liang, Pierre Baldi, Robert H Gilman, Joseph M Vinetz, Renée M Tsolis, Philip L Felgner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2864264?pdf=render

Internet

http://europepmc.org/articles/PMC2864264?pdf=render

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