Use of nivolumab for colon cancer with Lynch syndrome

Lynch syndrome (LS), which occurs as a result of the defects in DNA mismatch repair, is characterized by an increased risk of colon, endometrial and urinary tract cancers. It is known that in case of colorectal cancer, the presence of high-frequency microsatellite instability (MSI-H) is associated w...

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Bibliographic Details
Main Authors: G. A. Khakimov, A. A. Tryakin, G. G. Khakimova
Format: Article
Language:Russian
Published: IP Habib O.N. 2020-11-01
Series:Современная онкология
Subjects:
Online Access:https://modernonco.orscience.ru/1815-1434/article/viewFile/52595/36040