Chronic exposure to dopamine agonists affects the integrity of striatal D2 receptors in Parkinson's patients

We aimed to investigate the integrity and clinical relevance of striatal dopamine receptor type-2 (D2R) availability in Parkinson's disease (PD) patients. We studied 68 PD patients, spanning from early to advanced disease stages, and 12 healthy controls. All participants received one [11C]raclo...

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Bibliographic Details
Main Authors: Marios Politis, Heather Wilson, Kit Wu, David J. Brooks, Paola Piccini
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158217302012