Fear Extinction and Predictive Trait-Like Inter-Individual Differences in Rats Lacking the Serotonin Transporter

Fear Extinction and Predictive Trait-Like Inter-Individual Differences in Rats Lacking the Serotonin Transporter

Anxiety disorders are associated with a failure to sufficiently extinguish fear memories. The serotonergic system (5-hydroxytryptamine, 5-HT) with the 5-HT transporter (5-HTT, SERT) is strongly implicated in the regulation of anxiety and fear. In the present study, we examined the effects of SERT de...

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Bibliographic Details
Main Authors: Maria Willadsen, Metin Uengoer, Anna Sługocka, Rainer K.W. Schwarting, Judith R. Homberg, Markus Wöhr
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
fear conditioning
freezing
ultrasonic vocalizations
alarm calls
novelty-seeking
anxiety
Online Access:https://www.mdpi.com/1422-0067/22/13/7088

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