Daily dosing of rifapentine cures tuberculosis in three months or less in the murine model.

Daily dosing of rifapentine cures tuberculosis in three months or less in the murine model.

Availability of an ultra-short-course drug regimen capable of curing patients with tuberculosis in 2 to 3 mo would significantly improve global control efforts. Because immediate prospects for novel treatment-shortening drugs remain uncertain, we examined whether better use of existing drugs could s...

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Bibliographic Details
Main Authors: Ian M Rosenthal, Ming Zhang, Kathy N Williams, Charles A Peloquin, Sandeep Tyagi, Andrew A Vernon, William R Bishai, Richard E Chaisson, Jacques H Grosset, Eric L Nuermberger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-12-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC2140085?pdf=render

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http://europepmc.org/articles/PMC2140085?pdf=render

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