Dynamic Regulation of a Ribosome Rescue Pathway in Erythroid Cells and Platelets
Protein synthesis continues in platelets and maturing reticulocytes, although these blood cells lack nuclei and do not make new mRNA or ribosomes. Here, we analyze translation in primary human cells from anucleate lineages by ribosome profiling and uncover a dramatic accumulation of post-termination...
Main Authors: | Eric W. Mills, Jamie Wangen, Rachel Green, Nicholas T. Ingolia |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-09-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124716311974 |
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